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目的探讨血清hs-CRP、sICAM-1、ECP及TNF-α水平检测在支气管哮喘中的检测价值。方法选取2008年9月至2011年10月于本院进行治疗的27例支气管哮喘患者为观察组,同时选取同期的27名健康体检人员为对照组,后将两组人员的血清hs-CRP、sICAM-1、ECP及TNF-α水平进行检测及比较。结果观察组的血清hs-CRP、sICAM-1、ECP及TNF-α水平均高于对照组,且急性发作期患者明显高于缓解期患者,P均<0.05,均有显著性差异。结论血清hs-CRP、sICAM-1、ECP及TNF-α水平检测在支气管哮喘中的检测价值较高,且可反应疾病的发展转归。
Objective To investigate the detection of serum hs-CRP, sICAM-1, ECP and TNF-α levels in bronchial asthma. Methods Twenty-seven patients with bronchial asthma who were treated in our hospital from September 2008 to October 2011 were selected as the observation group. At the same time, 27 healthy people were selected as the control group. The serum hs-CRP, sICAM-1, ECP and TNF-α levels were detected and compared. Results The levels of hs-CRP, sICAM-1, ECP and TNF-α in the observation group were significantly higher than those in the control group, and the patients in the acute phase were significantly higher than those in the remission phase, both P <0.05. Conclusion The detection of serum hs-CRP, sICAM-1, ECP and TNF-α levels in bronchial asthma is of high value and can reflect the development of the disease.