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目的:对县乡两级医疗机构门急诊使用抗菌药物进行综合干预,促进合理使用。方法:依照《抗菌药物临床应用指导原则》等法规,在各医疗机构实施综合干预措施。调研干预前1个时段、干预后2个时段各医疗机构抗菌药物使用、管理情况,进行对照研究。结果:综合干预管理后,各医疗机构完善了抗菌药物使用管理制度;3个时段门急诊处方抗菌药物不合理例次率,县级医院为14.13%、10.69%、7.25%,乡镇卫生院为23.65%、16.17%、14.38%,差异均有显著统计学意义(P<0.01)。结论:通过对县乡两级医疗机构抗菌药物使用管理的综合干预,降低了门急诊抗菌药物使用率,提高了合理使用率。
Objective: To comprehensively intervene the use of antibacterials in outpatient and emergency department of county and township medical institutions to promote rational use. Methods: According to the “Guiding Principles for Clinical Application of Antibacterials” and other laws and regulations, comprehensive interventions were implemented in various medical institutions. To investigate the use and management of antibiotics in various medical institutions at one time before intervention and two periods after intervention, and to conduct a comparative study. Results: After the comprehensive intervention management, the medical institutions improved the management system of antimicrobial use. The irrational cases of antimicrobial agents in emergency department at three periods were 14.13%, 10.69% and 7.25% respectively in county hospitals and 23.65 in township hospitals %, 16.17% and 14.38%, respectively, with significant difference (P <0.01). Conclusion: Through the comprehensive intervention of antimicrobial use management in medical institutions at county and township level, the utilization rate of antimicrobial drugs in emergency department and emergency department is reduced and the reasonable utilization rate is increased.