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用两种灌注显像剂,对84例老年中枢神经系统疾病患者行单光子断层显像(SPEC)研究。其中脑血管疾病53例,痴呆25例(AD17例,MID8例),帕金森氏病6例。79例进行了CT检查并作了比较,结果表明,SPECT脑显像对脑血管疾病有较高的诊断价值。93.3%脑梗塞患者SPECT显像有阳性发现,图像特征为病灶处血流灌注减少所致的放射性减低区,与CT相符,但范围较CT为大。在TIA、脑供血不足及脑动脉硬化中均见到有局部血流减少的表现,较CT为灵敏,但脑出血阳性率略逊于CT。痴呆症的SPECT改变在AD和MID中各有其特征性改变。大多数帕金森氏病患者的大脑和基底节可见到血流减低区,其CT改变不明显。
Using two kinds of perfusion imaging agents, 84 cases of senile central nervous system diseases were studied by single photon tomography (SPEC). Including 53 cases of cerebrovascular disease, dementia in 25 cases (AD17 cases, MID8 cases), Parkinson’s disease in 6 cases. 79 cases were examined by CT and compared, the results show that SPECT brain imaging has a higher diagnostic value of cerebrovascular disease. 93.3% of patients with cerebral infarction SPECT imaging positive findings, the lesion characterized by reduced perfusion was reduced radioactive lesions, consistent with the CT, but a larger range than CT. In TIA, cerebral insufficiency and cerebral arteriosclerosis are seen in the performance of local blood flow reduction, more sensitive than CT, but the positive rate of cerebral hemorrhage slightly worse than CT. SPECT changes in dementia have their own characteristic changes in AD and MID. Most patients with Parkinson’s disease in the brain and basal ganglia seen reduced blood flow area, the CT change was not obvious.