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目的探讨IGR健康相关生命质量状况对糖尿病发病的影响。方法基于1136名的人群队列,采用SF-12量表进行生命质量状况评价,并跟踪和总结两年后IGR患者转归情况,并应用泊松回归模型探讨生命质量状况与IGR转归的关系。结果相对高、较低生理得分将增加糖尿病发病风险(中高RR=0.92,中低RR=1.21,低RR=1.69,Ptrend<0.001);相对高心理得分、较低心理得分也将增加糖尿病发病的风险(中高RR=1.15,中低RR=1.15,低RR=1.51,Ptrend<0.001)。结论 IGR患者生命质量状况对糖尿病发生具有一定的预测功能。
Objective To investigate the impact of IGR health-related quality of life on the incidence of diabetes. Methods Based on 1136 cohorts of patients, the quality of life condition was evaluated by SF-12 scale. The outcomes of IGR patients were tracked and summarized two years later. The relationship between the quality of life and the outcome of IGR was analyzed by Poisson regression model. The results were relatively high with lower physiologic scores increasing the risk of developing diabetes (high RR = 0.92, low RR = 1.21, low RR = 1.69, Ptrend <0.001); lower psychologic scores also increased diabetes mellitus Risk (RR RR = 1.15, RR = 1.15, RR = 1.51, Ptrend <0.001). Conclusion The quality of life of patients with IGR has certain predictive value for the occurrence of diabetes mellitus.