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众所周知,代谢性疾病多为长期慢性病,在多年以后才表现出明显的临床症状。例如,随着胰岛素缺乏时间的延长,患者才能被诊断为2型糖尿病或高胰岛素血症。目前,临床和实验室可通过检测一些指标(如体质指数或空腹血糖)来预测糖尿病发生危险,但是这些指标只反映疾病的表面状态,无法显示疾病本身的病理生理机制。然而通过对生物样本代谢图谱研究能够更早地发现与糖尿病相关的危险因素,并能够通过早期干预来预防糖尿病的发生和发展,这是目前学术
As we all know, mostly metabolic diseases are chronic chronic diseases, showing obvious clinical symptoms after many years. For example, a patient can be diagnosed with type 2 diabetes or hyperinsulinemia as insulin deficiency is prolonged. Currently, clinics and laboratories can predict the risk of diabetes by detecting some indicators (such as body mass index or fasting blood glucose), but these indicators only reflect the surface status of the disease, can not display the pathophysiology of the disease itself. However, by studying the metabolic profiling of biological samples, we can find the risk factors related to diabetes earlier and prevent the occurrence and development of diabetes through early intervention, which is the current academic