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目的探讨小剂量肝素钙皮下注射合用中药治疗栓前状态,近期临床疗效及安全性。方法经系统检查符合高粘血症合并高脂血症30例。(1)肝素钙皮下脂肪层注射,一次7500U,每日一次。(2)中药治疗:丹参150g,何首乌150g,共为细末,每次10g,温开水冲服,每日2次。上述中西药治疗15d为一疗程,可行1~2疗程。观察治疗前后临床症状、体征、纤维蛋白原、血浆粘度、血小板、胆固醇、甘油三酯、心电图、凝血时间测定的改善情况。结果显效66.7%(20/30);有效33.3%(10/30),总有效率100%。治疗后临床症状及体征均有显著改善,改善率均为100%。9例显示S-T缺血心电图均有明显改善。治疗后化验检查与治疗前相比除血小板无明显改变外,纤维蛋白原、胆固醇、甘油三酯均差异有显著性。结论小剂量肝素钙皮下注射合用中药是治疗高粘血症、高脂血症、栓前状态、预防血栓形成的安全、有效、理想的治疗方法。
Objective To investigate the clinical efficacy and safety of low dose heparin calcium subcutaneous injection combined with traditional Chinese medicine in the treatment of preeclampsia. Methods According to the systematic examination, 30 patients with hyperviscosity and hyperviscosity were included. (1) heparin calcium subcutaneous fat injection, once 7500U, once daily. (2) Chinese medicine treatment: Salvia 150g, Polygonum 150g, a total of fine, each 10g, warm boiled water, 2 times a day. The Chinese and Western medicine treatment for 15d for a course of treatment, feasible 1 to 2 courses. Before and after treatment to observe the clinical symptoms, signs, fibrinogen, plasma viscosity, platelets, cholesterol, triglycerides, ECG, clotting time measured improvement. The results were markedly effective 66.7% (20/30); effective 33.3% (10/30), the total efficiency of 100%. After treatment, clinical symptoms and signs were significantly improved, the improvement rate was 100%. 9 cases showed S-T ischemia ECG were significantly improved. After treatment, compared with before treatment, no significant changes in platelet count, fibrinogen, cholesterol, triglycerides were significantly different. Conclusion Low-dose heparin calcium subcutaneous injection of traditional Chinese medicine is the treatment of hyperviscosity, hyperlipidemia, pre-suppository state, prevention of thrombosis safe, effective and ideal treatment.