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克罗米芬(CC)治疗男子不孕症的效力说法不一。许多研究证实用CC治疗患有特发性无明显畸形、精子活动力差(OTA)的病人,可增加其精子数目,而其他一些研究却证实精子质量无任何好转。这种矛盾结果的原因似乎是由于选择病人,治疗剂量和治疗期限标准的困难。CC似乎通过促性腺激素间接作用于生殖上皮。因为人的精子生成和转运是3个月。所以,有人建议用CC治疗男性需几个月。最近研究表明每日25mg要比以前报道的较高剂量更有效。作者目的在于检验较低剂量CC在精子质量方面产生较好的假说。作者将89例精子缺乏(多数属于OTA)者中卵泡生成激素(FSH)水
Different efficacy of clomiphene citrate (CC) in the treatment of infertility in men. Many studies have demonstrated that the use of CC in patients with idiopathic no significant deformity, poor sperm motility (OTA) patients, can increase the number of sperm, while others have confirmed no improvement in sperm quality. The reason for this paradoxical outcome seems to be the difficulty of choosing a patient, the dose to be treated, and the duration of the treatment period. CC seems to act indirectly on the reproductive epithelium through gonadotropins. Because human sperm production and transshipment is 3 months. Therefore, it is suggested that men take CC for several months. Recent studies show that 25 mg daily is more effective than the higher doses previously reported. The authors aim to test the hypothesis that lower doses of CC produce better sperm quality. The authors of 89 cases of sperm deficiency (mostly OTA) who follicle-producing hormone (FSH) water