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对采用主动免疫治疗获成功的２２对原因不明性习惯性流产夫妇，作了治疗前后患者抗丈夫淋巴细胞毒抗体和混合淋巴细胞培养（ＭＬＣ）观察。发现治疗后大部分患者没有出现抗丈夫淋巴细胞毒抗体，提示细胞毒抗体与治疗是否成功无必然联系。ＭＬＣ结果表明，主动免疫治疗在患者中诱发了免疫抑制，且这种抑制是非特异针对丈夫的。因为治疗后，患者对丈夫，患者对无关男性的ＭＬＣ刺激指数均显著下降，同时伴有血清抑制因子升高，两者与治疗前相比均有显著差异（Ｐ＜０．０１）。提示细胞免疫参与了免疫抑制。诱发免疫抑制可能是主动免疫治疗获得成功的机制之一。
Of the 22 pairs of unexplained habitual abortion couples who were successfully treated with active immunotherapy, the patients were tested for anti-husband lymphocyte cytotoxic antibody and mixed lymphocyte culture (MLC) before and after treatment. Found that most patients after treatment did not appear anti-husband anti-lymphocyte antibodies, suggesting that the cytotoxic antibodies and treatment is not necessarily linked to the success. MLC results show that active immunotherapy induces immunosuppression in patients and that this inhibition is non-specific to the husband. Because after treatment, the patients with husbands, patients with unrelated males MLC stimulation index were significantly decreased, accompanied by elevated serum levels of both, both compared with before treatment were significantly different (P <0.01). Suggesting that cellular immunity is involved in immunosuppression. Induction of immune suppression may be one of the mechanisms by which active immunotherapy may be successful.