论文部分内容阅读
目的:探讨结节性胃炎的临床特点及与幽门螺杆菌(Hp)的关系,以提高对其的认识。方法:观察诊断为结节性胃炎患者的内镜、病理表现,以及Hp感染情况和根除治疗的效果。结果:33例结节性胃炎病例中,内镜下表现特点为:以胃窦部为主,大小均匀的结节样或颗粒样改变。Hp感染率93.9%,病理检查提示胃黏膜呈中度至重度炎症改变,淋巴滤泡发生率69.6%。明显高于其他胃炎。经给予质子泵抑制剂为基础的三联疗法根除治疗后,随着Hp的根除。临床症状消失,淋巴滤泡消失,病理炎症程度减轻。结论:结节性胃炎为Hp感染的一种特殊征象,是慢性胃炎的一种特殊内镜下表现,是Hp感染的内镜指标,提示对结节性胃炎应考虑Hp根除治疗。
Objective: To investigate the clinical features of nodular gastritis and its relationship with Helicobacter pylori (Hp) so as to enhance its understanding. Methods: To observe the endoscopic and pathological findings of patients diagnosed as nodular gastritis and the effect of Hp infection and eradication therapy. Results: Of the 33 cases of nodular gastritis, endoscopic features were as follows: nodular or granuliform changes mainly of gastric antrum. Hp infection rate of 93.9%, pathological examination showed mild to moderate gastric mucosal inflammation changes, the incidence of lymphatic follicles 69.6%. Obviously higher than other gastritis. After being given proton pump inhibitor-based triple therapy, eradication therapy followed Hp eradication. Clinical symptoms disappear, lymphoid follicles disappear, reduce the degree of pathological inflammation. Conclusion: Nodular gastritis is a special sign of Hp infection and is a special endoscopic manifestation of chronic gastritis. It is an endoscopic indicator of Hp infection, suggesting that Hp eradication should be considered for nodular gastritis.