幽门螺杆菌(HP)是胃肠道中的常见致病菌,是胃癌的高危因素。HP通过自身突变,可以避免被先天性免疫细胞上模式识别受体(patten recognition receptors,PRRs)所识别,同时促使机体产生调节性T细胞(Treg),抑制机体的体液免疫及细胞免疫,逃避获得性免疫反应,维持自身持久的感染能力。HP感染时所产生的Treg可以有效的抑制哮喘,慢性炎症反应和自身免疫疾病的发生,HP正是利用这 Helicobacter pylori (HP) is a common pathogen in the gastrointestinal tract and is a risk factor for gastric cancer. By its own mutation, HP can avoid being recognized by the pattern recognition receptors (PRRs) on innate immune cells, and at the same time promote the production of regulatory T cells (Tregs), suppress humoral and cellular immunity of the body, and evade obtainment Immune response to maintain its long-lasting ability to infect. HP infected Treg produced by the effective suppression of asthma, chronic inflammatory reactions and autoimmune diseases, HP is the use of this