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目的 :观察脑囊虫病患者血清一氧化氮 ( NO)和 TNFα的水平并探讨其临床意义。方法 :用比色法和双抗夹心 ELISA检测了 3 0例脑囊虫病患者血清的一氧化氮 ( NO)和肿瘤坏死因子α( TNFα)水平。结果 :患者血清 TNFα含量为 ( 0 .66± 0 .1 2 )× 1 0 - 3ng/ L,与正常对照组的 ( 0 .1 1 8± 0 .0 51 )× 1 0 - 3ng/ L比较有极显著性差异 ( P<0 .0 1 ) ;血清 NO水平为 ( 2 7.77± 3 .77) μmol/ L,明显低于正常对照组的 ( 50 .0 4± 6.2 3 ) μmol/ L( P<0 .0 1 )。结论 :脑囊虫病患者机体免疫功能受抑制 ,免疫功能低下
Objective: To observe the levels of serum nitric oxide (NO) and TNFα in patients with cysticercosis and to explore its clinical significance. Methods: Serum levels of nitric oxide (NO) and tumor necrosis factor α (TNFα) in 30 patients with cysticercosis were detected by colorimetric assay and double-antibody sandwich ELISA. Results: The serum level of TNFα was (0.66 ± 0.12) × 10-3 ng / L, which was significantly lower than that of the control group (0.118 ± 0.051) × 10-3 ng / L (2 7.77 ± 3.77) μmol / L, which was significantly lower than that of the control group (50.0 ± 6.2 ± 3) μmol / L (P <0.01) P <0 .0 1). Conclusion: The patients with cerebral cysticercosis have suppressed immune function and immune function