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层粘素（亦称层粘连蛋白）在恶性肿瘤的浸润和转移中起着重要的作用，恶性细胞表面有大量的层粘素受体，而且能更多、更快地与层粘素结合。人工合成的层粘素五肽酪氨酰－异亮氨酰－甘氨酰－丝氨酰－精氨酸（ＹＩＧＳＲ）肽能够与肿瘤相关的高亲和性层粘素受体结合放射性核素标记ＹＩＧＳＲ是一种很有发展潜力的、能够估计活体内肿瘤细胞转移潜能的、具有受体特异性的放射性药物。
Laminin (also known as laminin) plays an important role in the invasion and metastasis of malignant tumors, which contain a large number of laminin receptors on the surface of malignant cells and can bind laminin more rapidly and rapidly. The synthetic laminarin pentapeptide tyrosyl-isoleucyl-glycyl-seryl-arginine (YIGSR) peptide is capable of binding tumor-associated high-affinity laminin receptors to radionuclides Marker YIGSR is a promising, radiopharmaceutical with receptor specificity that can assess the metastatic potential of tumor cells in vivo.