论文部分内容阅读
用放射免疫法对10例慢性肾功能不全患者和20例正常人进行血清T_3、T_4和TSH浓度测定,结果肾功能不全患者血清T_3浓度明显低于正常人(P<0.001),血清T_3浓度与血清BuN、Cr、24小时尿蛋白总量、尿白蛋白、尿β_2-微球蛋白浓度呈明显负相关(P<0.025～0.001),血清T_4、TSH浓度与正常人无显著性差异;尿毒症患者血清T_3、T_4浓度明显低于氮质血症患者(P分别<0.05,<0.025)。说明血清T_3、T_4浓度变化对疗效与预后判断有一定意义。
Serum levels of T_3, T_4 and TSH were measured by radioimmunoassay in 10 patients with chronic renal failure and 20 normal controls. Results Serum T_3 concentrations in patients with renal insufficiency were significantly lower than those in normal controls (P <0.001) Serum BuN, Cr, 24-hour urinary protein, urinary albumin, urinary β_2-microglobulin concentration was negatively correlated (P <0.025 ~ 0.001), serum T_4, TSH concentrations and normal people no significant difference; uremia Serum levels of T_3 and T_4 were significantly lower in patients with azotemia (P <0.05, <0.025, respectively). Description of serum T_3, T_4 concentration changes on the efficacy and prognosis of a certain significance.