目的 研究胆囊结石合并胆囊炎术后实施精细化护理干预的效果。方法 选取2019年3月至2020年3月于我院进行胆囊结石合并胆囊炎术的患者112例，随机分成观察组与对照组，每组患者各56例。对照组患者采取常规的护理模式，观察组患者在常规护理模式的基础上采取精细化护理干预，对比干预后两组患者的护理效果，包括干预后患者下床活动的时间、肛门排气的时间、进食的时间、住院的时间；对比干预后两组患者及其家属对此次护理服务的满意度。结果 干预后观察组患者下床活动的时间、肛门排气的时间、进食的时间、住院的时间皆短于对照组（P“,”Objective To study the effect of refined nursing intervention after gallbladder stones combined with cholecystitis. Methods A total of 112 patients who underwent gallbladder stones and cholecystitis in our hospital from March 2019 to March 2020 were randomly divided into observation group and control group， with 56 patients in each group. The patients in the control group took the conventional nursing mode， and the patients in the observation group took refined nursing intervention on the basis of the conventional nursing mode. The nursing effect of the two groups of patients after the intervention was compared， including the time for the patient to get out of bed and the time for anal exhaust after the intervention. The time of eating， the length of hospitalization; compare the satisfaction of the two groups of patients and their families with the nursing service after the intervention. Results After the intervention， the time for patients in the observation group to get out of bed， the time to exhaust anus， the time to eat， and the time to stay in the hospital were shorter than those of the control group (P＜0.05); after the intervention， patients in the observation group and their family members took care of the nursing service Satisfaction was higher than the control group (P＜0.05). Conclusion The implementation of refined nursing intervention after gallbladder stones combined with cholecystitis can improve the nursing effect and the patients\' satisfaction with nursing. The effect is very good and it is worthy of popularization and application.