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目前已日益清楚地认识到,大肠杆菌是急性腹泻的病因之一。对于大肠杆菌的特殊血清型在急性婴幼儿腹泻中的病原学意义已有广泛的研究,但在成人腹泻中的意义研究不多。本文报道130例成人急性腹泻的临床和细菌学研究结果。 130例患者中,男91例,女39例。年龄16～70岁(平均29.4岁),62%的患者属于20～40岁年龄组,23%属15～20岁年龄组。55%的患者在6～7月份发病,23%在8～9月份发病。这些患者都是发病不到72小时,每天大便在4次以上。对所有患者都作了临床评价,大便标本肉眼检查、镜检和培养分离病原菌。根据临床病情可把这些患者分为三型:①轻度:排尿量正常,无失水征象;②中度:排尿量正常,仅有轻度到中度失水,收缩压在100mmHg以上;③重度:显著失水,伴或不伴周围循环衰竭征,少尿或尿闭,收缩压在100mmHg以下。78%的患者属中度,仅6%的患者属重度。大便肉眼检查:93%为水样便,7%为半固体大便。大便镜检:84%见脓细胞,
It has become increasingly clear that Escherichia coli is one of the causes of acute diarrhea. Etiological significance of E. coli specific serotypes in acute infantile diarrhea has been extensively studied, but little is known about it in adult diarrhea. This article reports the clinical and bacteriological findings of 130 adult patients with acute diarrhea. Of 130 patients, 91 were males and 39 were females. Aged 16-70 years (mean, 29.4 years), 62% of patients were in the 20-40 year age group and 23% were in the 15-20 year age group. 55% of patients in June and July onset, 23% onset in August and September. These patients are less than 72 hours of onset, stool more than 4 times a day. All patients were clinically evaluated, stool specimens were examined by naked eye, microscopic examination and culture to isolate pathogens. According to clinical conditions, these patients can be divided into three types: ① mild: normal urinary output, no signs of water loss; ② moderate: normal urination, mild to moderate dehydration, systolic blood pressure above 100mmHg; ③ Severe: significant dehydration, with or without signs of peripheral circulation failure, oliguria or urinary closure, systolic blood pressure below 100mmHg. 78% of patients are moderate, only 6% of patients are severe. Stool eye examination: 93% of watery stool, 7% of semi-solid stool. Stool microscopy: see 84% of pus cells,