0　引　　言阿糖胞苷(HDAC)是治疗急性白血病的常用药物,利用其独特的药物动力学和作用机制而大剂量使用,可明显提高疗效,但由于大剂量阿糖胞苷比普通剂量阿糖胞苷用量高10多倍,故不良反应明显,所以做好HDAC化疗期及化疗后的护理是保证患儿顺利完成化疗的关键。我科自1996年起? 0 Introduction Cytarabine (HDAC) is a commonly used drug for the treatment of acute leukemia, using its unique pharmacokinetics and mechanism of action and high-dose, can significantly improve the efficacy, but because of high doses of cytarabine than normal dose of sugar Cytidine dosage 10 times higher, so the adverse reactions were obvious, so do HDAC chemotherapy and chemotherapy after care is to ensure the successful completion of chemotherapy in children with the key. Our department since 1996?