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目的：探讨肝素经纤支镜给药的血药浓度及其辅助抗炎作用。方法：二组共57例慢性呼吸道炎症患者在基础抗炎下分别予肝素性理盐水经纤支镜灌注。结果：以单一剂量肝素12500u经纤支镜给药，血中有低浓度肝素存在并维持14d以上。临床总有效率达96．5％，疗效高于生理盐水对照组（P＜0．01）。结论：小剂量肝素经纤支镜给药是治疗慢性呼吸道炎症安全而有效的手段。
Objective: To investigate the blood concentration of heparin via bronchofiberscopy and its auxiliary anti-inflammatory effect. Methods: Two groups of 57 patients with chronic respiratory inflammation under basic anti-inflammatory were given heparin saline saline perfusion by bronchofiberscopy. Results: A single dose of heparin 12500u by fiberoptic bronchoscopy, low blood concentration of heparin exists and maintain 14d above. The total effective rate of clinical 96.5%, higher efficacy than the saline control group (P <0.01). Conclusion: The small dose of heparin via fiberoptic bronchoscopy is a safe and effective treatment of chronic respiratory inflammation.