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目的 了解惠州市人群麻疹免疫状况 ,探讨预防控制对策。方法 选择本地人口 398人进行人群麻疹抗体水平调查 ,监测对象分为 6个年龄组 ,男女比例接近 1∶1;选择 8～ 12月龄婴儿开展麻疹疫苗(MV)免疫成功率及母传麻疹抗体水平监测 ,同时调查 4岁儿童麻疹疫苗再免成功率。结果 2～ 4 1岁人群抗体阳性率 92 7% ,几何平均滴度 (GMT)为 1∶996 8,不同年龄组人群GMT水平、抗体阳性率差异有统计学意义 ;婴儿母传抗体阳性率和GMT分别为 2 0 0 %和 1∶5 12 ;麻疹疫苗初免成功率和再免成功率分别为 88 0 %和 78 5 %。结论 为加快惠州市的麻疹控制步伐 ,建议提高MV常规免疫接种覆盖率 ,减少免疫空白人群 ,开展 1～ 14岁人群的MV强化免疫活动及育龄期妇女MV免疫接种
Objective To understand the status of measles immunity in Huizhou and to explore the preventive and control strategies. Methods A total of 398 local population were selected for measles antibody test. The monitoring subjects were divided into 6 age groups with a ratio of 1: 1. The success rate of measles vaccine (MV) and measles antibody of mother to child Level monitoring, while 4-year-old children measles vaccine re-test success rate. Results The positive rate of antibody was 92.7% and the geometric mean titer (GMT) was 1:996 between 2 ~ 4 years old. The GMT level and the positive rate of antibody in different age groups were significantly different GMT were 200% and 1: 5 12 respectively; the success rate of initial immunization and the rate of re-immunity of measles vaccine were 88 0% and 78 5% respectively. Conclusion In order to speed up the measles control in Huizhou, it is suggested to increase the routine immunization coverage of MV and reduce the population of immunocompromised persons, and to carry out the MV immunization activities and MV immunization of women of childbearing age in 1 ~ 14 years old