麻风病时,皮神经是麻风菌感染的靶组织之一,同时累及躯体和自主神经系统。早期体征是不出汗,继之温、痛觉消失。各型麻风最早的周围神经改变见于无髓神经纤维,以后才是小的有髓神经纤维,最后较大的有髓神经纤维也受累。动物模型发现小鼠接种麻风杆菌后第四个月就呈现弥漫性周围神经 Leprosy, the cutaneous nerve is one of the target tissues of leprosy infection, involving both the body and the autonomic nervous system. Early signs are not sweating, followed by warm, pain disappeared. The earliest peripheral changes of leprosy were found in unmyelinated nerve fibers, and later in small myelinated nerve fibers. Finally, the larger myelinated nerve fibers were also involved. Animal models found diffuse peripheral nerves appeared in the fourth month after inoculation in mice