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肺动脉高压(PH)是一种严重威胁人类健康的疾病,以肺血管阻力进行性升高为特征,最终导致右心功能衰竭,产生一系列临床症状,主要病理改变为血管收缩、重塑及血栓形成等。PH的血流动力学定义是肺动脉平均压>25mmHg。随着对PH发病机制认识的深入,针对PH的发病各环节的治疗即靶向治疗不断取得进展,靶向治疗的药物主要包括前列环素及其类似物、内
Pulmonary hypertension (PH) is a disease that is a serious threat to human health and is characterized by progressive elevation of pulmonary vascular resistance, which eventually leads to right heart failure and a series of clinical symptoms. The main pathological changes are vasoconstriction, remodeling and thrombus Formed and so on. The hemodynamic definition of PH is the mean pulmonary artery pressure> 25 mmHg. With the deepening of the understanding of the pathogenesis of PH, the PH treatment for all aspects of the disease that is targeted to continue to progress in the treatment of targeted drugs include prostacyclin and its analogs,