氧化应激反应在阿尔茨海默病(AD)的发生中具有重要作用。绿茶及绿茶多酚作为公认的抗氧化剂,可减轻脂质过氧化反应,抑制氧化性DNA损伤,进而调节细胞凋亡过程,并可能抑制胆碱酯酶活性,干预淀粉样前体蛋白的生物合成,减轻淀粉样蛋白的沉积,从而干预AD的病理过程,发挥神经保护作用。 Oxidative stress plays an important role in the development of Alzheimer’s disease (AD). Green tea and green tea polyphenols are recognized as antioxidants, can reduce lipid peroxidation, inhibit oxidative DNA damage, and then regulate apoptosis process, and may inhibit cholinesterase activity and interfere with amyloid precursor protein biosynthesis. , reduce the deposition of amyloid, thereby interfering in the pathological process of AD, play a neuroprotective role.