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一、诊断标准: SLE的诊断标准过去是以美国风湿病协会1971年发表的诊断手册(表Ⅰ)为标准的。最近,Tan等人考虑到免疫学检查的进展以及疾病分类的变更,对原诊断标准进行了研究与修改,提出了新的诊断标准(表Ⅱ)。据报道,新诊断标准的敏感性、特异性均为96%,而旧标准的敏感性则为88%、特异性为95%。相比结果,特异性虽差别不大,但敏感性却有显著提高。故被认为,新的诊断标准是一种更进步的标准。
First, the diagnostic criteria: SLE diagnostic criteria used to be based on the American College of Rheumatology diagnostic manual published in 1971 (Table I) as a standard. Recently, Tan et al. Studied and modified the original diagnostic criteria and proposed new diagnostic criteria (Table II), taking into account the progress of immunological tests and changes in classification of diseases. The sensitivity and specificity of the new diagnostic criteria are reported to be 96%, compared with 88% and 95% specificity for the older criteria. Compared with the results, although the difference is not significant, but the sensitivity has increased significantly. It is therefore believed that the new diagnostic criteria is a more advanced standard.