恶性胸腔积液是肿瘤晚期的常见并发症。一旦发生,患者平均生存期仅3.1个月,84%的患者在确诊后6个月内死亡。采用胸腔内穿刺置管引流,结合胸腔内用药是其主要的治疗方法,可以缓解症状,改善生活质量。化疗药物兼具抑制胸腔内肿瘤细胞和产生胸腔粘连的作用,是最常选用的胸腔内治疗 Malignant pleural effusion is a common complication of advanced cancer. In the event of an average survival of only 3.1 months, 84% of patients died within 6 months of diagnosis. The use of intrathoracic puncture catheter drainage, combined with intrathoracic medication is the main treatment, can relieve symptoms and improve the quality of life. Chemotherapy drugs both inhibit intrathoracic tumor cells and the role of the production of pleural adhesions, is the most commonly used in the treatment of thoracic cavity