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应用多中心研究方法观察了赛姆斯口服液(胸腺蛋白)治疗221例消化性溃疡(胃溃疡51例,十二指肠球部溃疡170例)的疗效.赛姆斯口服液6 ml(30 mg),2次/d,每周复诊1次,了解症状变化情况及服药反应,4周后复查胃镜.结果显示:胃溃疡愈合率74.5%,总有效率94.1%,腹痛消失率75.2%;十二指肠溃疡愈合率65.9%,总有效率82.4%,腹痛消失率75.2%.服药过程中无明显不良反应.本研究表明,赛姆斯口服液对治疗消化性溃疡有明显疗效,尤以治疗胃溃疡疗效更显著.
The effect of Sims oral liquid (thymus protein) on 221 cases of peptic ulcer (51 cases of gastric ulcer and 170 cases of duodenal ulcer) was observed by multicentre study. Symi oral liquid 6 ml (30 mg) twice a day for 1 week to find out the symptom change and medication response, and to review the gastroscope after 4 weeks.The results showed that the healing rate of gastric ulcer was 74.5%, the total effective rate was 94.1% and the disappearance rate of abdominal pain was 75.2%. The healing rate of duodenal ulcer was 65.9%, the total effective rate was 82.4% and the disappearance rate of abdominal pain was 75.2% .There was no obvious adverse reaction during the medication.The study shows that Sims oral liquid has obvious curative effect on the treatment of peptic ulcer, especially Therapeutic effect of gastric ulcer even more significant.