白蛋白系从健康人血浆中分离提取,经艾滋病抗体检测阴性及60℃10小时加温灭活肝炎病毒制成.已广泛用于临床。文献报道,输注白蛋白后发生变态反应率为0.11％,总反应率为0.47～1.58％,(包括荨麻疹、寒战、发热和低血压等),多数症状轻微,经冶疗可恢复.而导致过敏性休克死亡者较罕见,现将静滴白蛋白致过敏性休克死亡1例报告如下. 病例介绍 患者,男,64岁,干部,因咳嗽,咳痰,气急,胸痛2月,于1992年11月16日入院,诊断:左侧肺炎、左侧陈旧性胸膜炎.患者对键霉毒有过敏史.给予消炎、抗痨、对症、支持等综合治疗一个月后病情基本稳定.12月17日11时予以10％的白蛋白100毫升静滴,每分钟20滴,输前肌注非那根25毫克.10分钟后病人突然出现寒战,呼吸急促,当时考虑是输液反应,立即停止静滴,吸氧、肌注非那根25毫克,安痛定2毫升。40分钟后,查体温39.5℃,脉搏130次/分,呼吸30次/分,血压由16/8kPa下降至11/6kPa,患者神志清、头晕、恶心、心悸、气短、口唇紫绀、脉搏微弱.医护人员立 Albumin isolated from healthy human plasma extracted by the AIDS antibody negative and 60 ℃ 10 hours heating inactivated hepatitis virus has been widely used in clinical. Reported in the literature, the albumin allergic reaction rate was 0.11%, the overall response rate was 0.47 ~ 1.58%, (including urticaria, chills, fever and hypotension, etc.), most of the symptoms were mild, the treatment can be restored. A case of anaphylactic shock leading to death is rare, the present intravenous albumin-induced anaphylactic shock and death were reported as follows.Patients, male, 64 years old, cadre, due to cough, sputum, shortness of breath, chest pain in February, in 1992 The patient was diagnosed with left pneumonia and old left pleurisy on November 16, 2006. The patient had a history of allergy to key poisoning, and the condition was basically stable after a month of comprehensive treatment such as anti-inflammatory, anti-asthma, symptomatic, supportive, etc. Dec. 17 100% intravenous infusion of 10% albumin, 20 drops per minute, and 25 mg of non-pre-infusion intramuscular injection.After 10 minutes, the patient suddenly appeared chills and shortness of breath. At that time, the infusion reaction was considered and stopped immediately , Oxygen, intramuscular injection of non-root 25 mg, Antongding 2 ml. 40 minutes later, the body temperature 39.5 ℃, pulse 130 beats / min, breathing 30 beats / min, blood pressure decreased from 16 / 8kPa to 11 / 6kPa, patients with clear consciousness, dizziness, nausea, palpitations, shortness of breath, lips cyanosis, weak pulse. Medical staff stand