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本文研究了十六种N-苯乙基甘氨酸和β苯乙胺衍生物的X射线光电子能谱(XPS).着重探讨了这些分子中不同N原子环境对其N_(?)结合能的影响,同时,用Pauling离子特性规则计算了这些分子中N原子上的电荷密度,实验N_(?)和Pauling计算原子电荷很好符合,从而对用磷酰基保护N-苯乙基甘氨酸上的氨基,作分子内的傅氏反应,合成三尖杉酯碱的母核——苯并氮杂环庚酮避免脱羰,保护基易脱去等反应机理提供实验与半经验的理论根据。
X-ray photoelectron spectroscopy (XPS) of sixteen N-phenethyl glycine and β-phenylethylamine derivatives was studied in this paper.The effects of different N atom environments on the N_ (Ⅱ) binding energy of these molecules were discussed emphatically, At the same time, the charge density of N atoms in these molecules was calculated by the Pauling ionic property rule. The experimental charge and Pauling calculated the atomic charge well, so that the phosphoryl group protected the amino group on N-phenylethylglycine. Intramolecular Fourier reaction, the synthesis of the mother nucleus of harringtonine - benzazepinone to avoid decarbonylation, the protective group is easy to take off the reaction mechanism to provide experimental and semi-empirical theoretical basis.