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作者报告了6例乏特氏壶腹乳头部癌采用局部切除治疗。患者平均年龄63.8岁,均因黄疸住院,病程1~2个月。2例经内镜活检明确诊断,4例在术中冰冻切片证实。肉眼所见肿瘤直径均在2cm之内。生存时间和肿瘤的病理状况有关。1例低分化腺癌和1例浸润性腺癌分别于术后16和20个月死于复发。2例乳头状癌中,1例生存5年以上,另1例28个月后死于其他病。1例高分化腺癌和1例粘液腺癌分别于术后29和46个月仍生存良好。局部切除只适用于合并高危因素或严重加杂病的老年患者,他们不能耐受胰十二指肠切除术,而肿瘤又很小可以局部切除。本文对手术操作进行了讨论。
The authors reported the use of local resection in 6 cases of pterygium in the ampulla of Vater. The average age of the patients was 63.8 years. All of them were hospitalized for jaundice and the duration of disease was 1 to 2 months. Two cases were diagnosed by endoscopic biopsy, and 4 cases were confirmed by intraoperative frozen section. The diameter of the tumor seen by the naked eye was within 2cm. The survival time is related to the pathological condition of the tumor. One case of poorly differentiated adenocarcinoma and one case of invasive adenocarcinoma died of recurrence at 16 and 20 months postoperatively, respectively. Of the 2 cases of papillary carcinoma, 1 survived more than 5 years and the other died of other diseases after 28 months. One case of well-differentiated adenocarcinoma and one case of mucinous adenocarcinoma survived well after 29 and 46 months, respectively. Local excision is only suitable for elderly patients with high-risk factors or severe miscellaneous diseases. They cannot tolerate pancreaticoduodenectomy, and the tumor is small enough to be removed locally. This article discusses surgical operations.