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目的比较通心络和美托洛尔治疗老年心力衰竭的临床疗效。方法选取2012年5月—2013年5月金坛区人民医院收治的老年心力衰竭患者180例,随机分为观察组92例与对照组88例。观察组给予通心络胶囊治疗,对照组给予美托洛尔治疗。比较两组患者治疗前后的心功能指标〔左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、心排血量(CO)〕及临床疗效。结果治疗前两组患者LVEF、LVESD、LVEDD及CO比较,差异无统计学意义(P>0.05);治疗后观察组患者LVEF、LVEDD、CO低于对照组,LVESD高于对照组,差异有统计学意义(P<0.05)。观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论通心络治疗老年心力衰竭的疗效优于美托洛尔,能够改善患者的心功能。
Objective To compare the clinical efficacy of Tongxinluo and metoprolol in the treatment of elderly patients with heart failure. Methods 180 elderly patients with heart failure admitted to Jintan District People’s Hospital from May 2012 to May 2013 were randomly divided into observation group (92 cases) and control group (88 cases). The observation group was given Tongxinluo capsule and the control group was treated with metoprolol. The left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), left ventricular end-systolic diameter (LVESD) and cardiac output (CO) were compared between the two groups before and after treatment. Results There was no significant difference in LVEF, LVESD, LVEDD and CO between the two groups before treatment (P> 0.05). After treatment, the LVEF, LVEDD and CO in the observation group were lower than those in the control group, and the LVESD was higher than that in the control group Significance (P <0.05). The total effective rate of observation group was higher than that of control group, the difference was statistically significant (P <0.05). Conclusion Tongxinluo treatment of senile heart failure is superior to metoprolol, can improve the patient’s cardiac function.