低血磷性佝偻病是一组由肾小管功能缺陷所致的疾病,包括维生素D依赖性佝偻病、肾小管酸中毒及范可尼氏综合征。前两者多由常染色体隐性遗传所致,后者多由肾小管泌氢不足或肾小管功能缺陷引起。其病因不同,故治疗亦有所差异。一、1,25—二羟维生素D_3:该药可提高肠粘膜对钙的吸收,促进肾小管对磷的重吸收,促进旧骨 Hypophosphatemic rickets is a group of diseases caused by renal tubular defects, including vitamin D-dependent rickets, renal tubular acidosis and Fanconi’s syndrome. The first two were mostly caused by autosomal recessive inheritance, which was mostly caused by inadequate renal tubular hydrogen secretion or renal tubular defects. The etiology is different, so the treatment is also different. First, 1,25-dihydroxy vitamin D_3: The drug can improve intestinal absorption of calcium to promote tubular reabsorption of phosphorus to promote the old bone