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目的查明河南油田所属新疆石油探区人群莱姆病感染与发病情况,为防治工作提供科学依据。方法采用普查方法进行流行病学调查,间接免疫荧光抗体法(IFAT)和酶联免疫吸附试验(ELISA)进行血清抗莱姆病螺旋体抗体检测。根据流行病学资料、临床表现和血清学检查结果进行病例诊断。统计学分析采用χ2检验。结果分别进行了5次调查,共计7956人,检测到抗莱姆病螺旋体抗体(IgG/IgM)阳性者1037份,感染率为12.07%～14.07%,平均感染率为13.03%。不同职业人群中,莱姆病感染率以野外勘探开发组最高(16.36%),野外建设施工组次之(12.63%),后勤服务组最低(7.58%),3组间感染率差异有统计学意义(χ2=101.1,P<0.01)。感染者中年龄最小6岁,最大61岁,但不同年龄组感染率差异无统计学意义(χ2=7.1,P>0.1)。诊断为莱姆病者665例,患病率为8.36%。结论河南油田新疆石油探区人群存在莱姆病感染,并有莱姆病的发生和流行,应加强莱姆病的防治,以保护其健康。
Objective To identify the prevalence and incidence of Lyme disease in oil exploration area of Xinjiang Oilfield owned by Henan Oilfield, and to provide a scientific basis for prevention and treatment. Methods The epidemiological investigation, indirect immunofluorescence antibody (IFAT) and enzyme-linked immunosorbent assay (ELISA) were used to detect the serum anti-Lyme disease antibody. According to epidemiological data, clinical manifestations and serological test results for case diagnosis. Statistical analysis using χ2 test. Results A total of 7956 people were investigated in 5 surveys. The number of anti-Leprosy antibody (IgG / IgM) positive was 1037, the infection rate was 12.07% -14.07% and the average infection rate was 13.03%. Among different occupational groups, the infection rates of Lyme disease were highest in field exploration and development group (16.36%), field construction and construction group (12.63%) and logistics service group (7.58%), the difference was statistically significant Significance (χ2 = 101.1, P <0.01). Among the infected persons, the youngest was 6 years old and the oldest was 61 years old, but there was no significant difference in infection rates among different age groups (χ2 = 7.1, P> 0.1). 665 patients diagnosed with Lyme disease, the prevalence was 8.36%. Conclusion There is Lyme disease infection in Xinjiang oil exploration area in Henan oilfield, and the occurrence and prevalence of Lyme disease. The prevention and cure of Lyme disease should be strengthened in order to protect their health.