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目的为探索急型克山病患者在较同步的短时间内暴死原因,拟提出一个假设,为科学研究建议一个方向。方法采用文献调查的方法,了解急型克山病患者暴死前重要的症状、体征,并与动物T-2毒素急性中毒实验中所出现的症状、体征进行比较。结果文献调查发现:1.急型克山病患者会在一个比较同步的短时间内发生暴死;2.患者死亡前有严重的呕吐,甚至混有胆汁;3.患者极度干渴,索饮大量凉水;4.出现一系列休克体征,如:血压进行性下降甚至到零,脉搏微弱、快速,直到扪不到。而这些症状在动物急性镰刀菌毒素中毒致死过程中亦是常见的,二者非常类似。结论急型克山病患者暴死的原因很可能是摄入霉变粮食中镰刀菌毒素急性中毒后,引起的低血容量休克
Objective To explore the causes of acute Keshan disease in a more synchronized short duration of violence, it is proposed a hypothesis for scientific research suggests a direction. Methods The methods of literature investigation were used to understand the important symptoms and signs of acute Keshan disease before the death and compared with the symptoms and signs of T-2 acute poisoning in animals. Results literature survey found: 1. Acute Keshan disease patients in a more synchronized short period of violent death; 2. Patients before the death of severe vomiting, and even mixed with bile; 3. Extreme thirst in patients, drink a lot of cold water; 4. A series of signs of shock, such as: progressive decline in blood pressure or even zero, pulse weak, fast, until palpable. These symptoms are also common in animal lethal death caused by acute Fusarium toxins, both of which are very similar. Conclusions The reason of acute Keshan disease in patients with sudden death is most likely the hypovolemic shock caused by the acute poisoning of Fusarium toxins