输血引起的急性肺损伤(TRAu)是血液治疗的严重并发症。在TRALI典型的发展过程中,其突出的特点是在输血后6小时内,于双肺水肿基础上进一步发展成为急性肺损伤。献血者或受血者体内的粒细胞抗体在TRALI发病机理中起重要作用,约80％由抗体介导的TRALI并发症中,在所提供的血制品的血浆中能够检测到粒细胞抗体。这些病例中,输入的中性 Transfusion-induced acute lung injury (TRAu) is a serious complication of blood therapy. In the typical development of TRALI, its outstanding feature is the further development of acute lung injury on the basis of double pulmonary edema within 6 hours after blood transfusion. Granulocyte antibodies in blood donors or recipients play an important role in the pathogenesis of TRALI, and about 80% of them can detect granulocyte antibodies in the plasma of the provided blood products in antibody-mediated TRALI complications. In these cases, the input is neutral