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Objective: To comprehensively evaluate the influencing factors of cough variant asthma (CVA) disease progression by meta-analysis, and to provide a reference for clinical work. Methods: comprehensive retrieve relevant assessment of cough variant asthma (CVA), the influence factors of disease progression of literature researchers a number of independent screens and quality evaluation, literature into literature, data extraction, into the literature of quality evaluation of the Newcastle - Ottawa (Newcastle - Ottawa Scale, NOS) Scale, Meta-analysis using RevMan 5.3 software, effect size for odds ratio (OR). Results: a total of 664 patients with CVA were included in the 7 English pieces of literature and 3 Chinese pieces of literature, among which 195 patients developed typical asthma.Family history of asthma [OR=14.12,95％Cl (7.79,25.59)],allergic condition [OR=5.70,95％Cl(2.02,16.13)],low FEV1/FVC[MD=-4.44,95％Cl (-5.28, -2.91)] were risk factors for the development of cough variant asthma (CVA).Conclusion: family history of asthma, allergic constitution, and low FEV1/FVC are risk factors for the progression of cough variant asthma (CVA). However, the mechanism of CVA progression to typical asthma is still unclear, and whether airway hyperresponsiveness is a risk factor is still controversial and needs to be further explored by clinicians and researchers.