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1.本文对我院1955～1982年收治的Addison病60例的临床资料作了分析,其中结核引起者占53.3％,自身免疫性占46.7％。 2.在对比分析各种实验室诊断方法的基础上,我们推荐简易水试验和皮质素水试验,其阳性率93％,且简便易行,适合于基层应用。 3.通过20例长期随访,观察了替代治疗的远期疗效,1例死于危象,8例治愈停药,其余仍服维持量糖皮质激素。1例住院期间发生危象和心跳骤停亦抢救成功。 4.就本组2例分别伴发糖尿病和甲亢问题,讨论了多腺性内分泌失调症的发病机理和治疗方法。
1. This article analyzes the clinical data of 60 cases of Addison’s disease treated in our hospital from 1955 to 1982, of which 53.3% were caused by tuberculosis and 46.7% were autoimmune. Based on comparative analysis of various laboratory diagnostic methods, we recommend the simple water test and cortisin water test, the positive rate of 93%, and simple, suitable for grass-roots applications. Through long-term follow-up of 20 cases, the long-term efficacy of alternative therapy was observed. One died of crisis and eight cases were cured. The rest of the patients were still given glucocorticoid. One case of crisis during hospitalization and cardiac arrest also rescued successfully. In this group of 2 cases were associated with diabetes and hyperthyroidism, discussed the pathogenesis and treatment of polyglandular endocrine disorders.