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一、体温调节与发热体温是维持生存必不可少的。它是靠体内热量的产生与释放间的平衡来维持恒定的。其中体温调节是通过反馈的方式实现的。也就是说,外部温度被皮肤的温度感受器所感知,传入中枢,与温度调定点(setPoiot)进行比较后,经末梢器官的调节使体温发生变化,此信息再由温度感受器反馈回中枢。体温的调节中枢位于间脑的PO/AH。此处有感知温度热、冷的两个神经元。当PO/AH温度升高时,热敏神经元的发射频率即增加,反之在PO/AH温度降低时,冷敏神经元的发射频率增加,并且,热敏神经元和冷敏神经元通过对散热和产热系统的双重支配来完成对体温的调控。例如去甲肾上腺素作用于PO/AH时,热敏神经元受到抑制,冷敏神经元被刺激,调定点向高温侧移动使体温升高。另外,已知,向PO/
First, body temperature regulation and fever body temperature is essential to maintain survival. It is by the body heat balance between the production and release to maintain a constant. Body temperature regulation is achieved by means of feedback. That is to say, the external temperature is sensed by the skin temperature sensor and then transmitted to the central nervous system. After being compared with the temperature set point, the body temperature changes through the adjustment of the terminal organ, and the information is fed back to the central center by the thermosensor. Body temperature regulation center located in the diencephalon PO / AH. There are two neurons that sense hot and cold temperatures. When the PO / AH temperature increases, the firing rate of the heat-sensitive neurons increases, whereas the firing frequency of the cold-sensitized neurons increases when the PO / AH temperature decreases, and the heat-sensitive and cold-sensitive neurons pass through Cooling and heat production system to achieve the dual control of body temperature regulation. For example, norepinephrine acts on PO / AH, heat-sensitive neurons are suppressed, cold-sensitive neurons are stimulated, set point to the high temperature side to move the body temperature. In addition, it is known that PO /