论文部分内容阅读
为了解犬咬伤者注射狂犬疫苗后抗体产生情况及维持时间,对18名同一狂犬咬伤者全程注射狂犬疫苗后二周、一年、五年分别在血清中和抗体测定(ELISA),结果显示:二周后18人抗体阳性率100%,GMT106(36-318)IU;一年时间:GMT19(6-174)IU;加强一针抗体水平迅速增长;GMT216(39-714)IU;五年时GMT8(4-56)IU。五年随访均健在,随着时间的延长抗体水平逐渐下降,但五年时间仍具有一定保护力,无一人转阴,说明国产疫苗(2.5IU/支)质量可靠,保护期理想。
In order to understand the antibody production and the duration of rabies vaccination in dogs with bite-bitten, 18 rabbits were vaccinated rabies vaccine for two weeks, one year and five years respectively in serum neutralizing antibody assay (ELISA) The results showed that: after two weeks, the positive rate of 18 human antibodies was 100%, the GMT106 (36-318) IU; one year: GMT19 (6-174) IU; Year GMT8 (4-56) IU. Five-year follow-up are healthy, with the extension of time antibody levels gradually declined, but five years still have some protection, no one negative, indicating that the domestic vaccine (2.5IU / support) reliable quality, the ideal period of protection.