随着化学工业的迅速发展,化学物引起的过敏型接触性皮炎(Allergic contact dermatitis)的发病率逐年增多,据美国劳工统计局(BLS)最近报告,职业性皮炎占职业病总数的40%以上,其中由化学物引起的过敏型接触性皮炎占60%左右,已成为当前美国最严重的职业危害之一。因此,及时预测和正确评价新化学物的接触致敏作用(Contact sensi- With the rapid development of the chemical industry, the incidence of chemical-induced Allergic contact dermatitis has been increasing year by year. According to the latest report of the U.S. Bureau of Labor Statistics (BLS), occupational dermatitis accounts for over 40% of the total number of occupational diseases. One of the chemicals caused by allergic contact dermatitis accounted for about 60%, has become one of the most serious occupational hazards in the United States. Therefore, timely prediction and correct evaluation of new chemical sensitization (Contact sensi-