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目的:探究脑脊液胆红素水平与病理性黄疸血清在新生儿病情评估中的作用。方法:采用回顾性分析的方法,将2014年1月~2015年1月期间在我院妇产科就诊的100例新生儿黄疸作为本次研究的对象,对这100例患儿进行病理性黄疸血清的测定,然后检测患儿脑脊液中的胆红素含量,对这两组患儿的脑脊液胆红素水平以及病理性黄疸水平进行比较分析,探究其在新生儿病情评估中的作用。结果:脑脊液胆红素水平与病理性黄疸中度组、重度组差异比较明显(P<0.05),有统计学意义;而且其胆红素含量高低与患儿的病情呈现正相关的关系(P<0.05),有统计学意义,黄疸血清与脑脊液胆红素的比值与患儿的病情没有关联性(P>0.05),无统计学意义。结论:脑脊液胆红素水平以及病理性黄疸血清可以作为新生儿病情评估的一个诊断标准,同时也可以判定为胆红素脑部敏感的诊断指标,对患儿的诊断及治疗有着重要的作用与价值,可以在临床医学中得以广泛地推广应用。
Objective: To explore the role of cerebrospinal fluid bilirubin and pathological jaundice in the assessment of neonatal condition. Methods: A retrospective analysis of 100 cases of neonatal jaundice in obstetrics and gynecology in our hospital from January 2014 to January 2015 as the object of this study, the 100 cases of children with pathological jaundice Determination of serum, and then detect the content of bilirubin in children with cerebrospinal fluid, the two groups of children with cerebrospinal fluid bilirubin levels and pathological jaundice levels were compared to explore its role in the assessment of neonatal condition. Results: The levels of bilirubin in cerebrospinal fluid and pathological jaundice were significantly different (P <0.05), and there was a significant difference between the two groups (P <0.05). Moreover, the level of bilirubin was positively correlated with the severity of the disease <0.05). There was no statistical significance in the relationship between jaundice serum and cerebrospinal fluid bilirubin and children’s disease (P> 0.05). Conclusion: CSF bilirubin levels and pathological jaundice serum can be used as a diagnostic criteria for the assessment of neonatal condition, and also can be used as a diagnostic indicator of brain sensitivity in bilirubin, which plays an important role in the diagnosis and treatment of children Value, can be widely applied in clinical medicine.