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目的了解食管癌高发区不同年龄段正常人群头发中微量元素含量及变化趋势。方法随机抽取林州市２５岁以上正常居民１２０名，按年龄分组，用原子吸收分光光度计（火焰法）和荧光法测定头发中铜、锌、钙、铁、硒等微量元素。结果林州市不同年龄组正常居民头发中锌、钙含量随年龄的增长，含量逐渐降低。相关系数分别是锌：ｒ＝－０．９０４２，钙：ｒ＝－０．９３８１，Ｐ均小于０．０１。铁元素在５５岁以下没有明显变化，５５岁以上显著降低，Ｐ＜０．０１。铜元素的变化是青年组较低，中年组略有升高，到５５岁以后又降低。硒元素除青年组与５５岁以上组有差别外，其余均无差异，Ｐ＞０．０５。结论头发中微量元素锌、钙、铁、硒等元素在５５岁以上的人群中均有明显降低，铜锌比例不稳定
Objective To understand the content of trace elements in the hair of normal population at different ages in esophageal cancer high incidence area and its changing trend. Methods A total of 120 normal residents over the age of 25 in Linzhou City were randomly selected and grouped according to age. Trace elements such as copper, zinc, calcium, iron, and selenium in hair were measured by atomic absorption spectrophotometry (flame method) and fluorescence spectrometry. Results The Zn and Ca contents in hair of normal residents in different age groups in Linzhou city increased with age, and the contents gradually decreased. The correlation coefficients were zinc: r = -0.9042, calcium: r = -0.9381, P all less than 0.01. There was no significant change in iron content below the age of 55 and a significant decrease over the age of 55, P<0.01. Changes in copper are lower in the youth group, slightly higher in the middle-aged group, and lower after the age of 55. There was no difference in selenium content between the young group and the 55-year-old group, P>0.05. Conclusion The trace elements zinc, calcium, iron, selenium and other elements in hair were significantly reduced in people over 55 years old, and the proportion of copper and zinc was not stable.