依那普利(乙丙脯氨酸,enalapril)是近几年用于治疗高血压和充血性心力衰竭的第二代血管紧张素转换酶抑制剂(ACEI)。研究发现该药引起咳嗽的发生率≥1%。作者回顾性分析了该药诱发咳嗽的发生率、临床特征及预后。病人和方法作者将前3年用过依那普利治疗的209例列为调查对象。全部病人于依那普利治疗开始后,随访至少3个月。通过查阅病历及与病人电话联 Enalapril is the second-generation angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension and congestive heart failure in recent years. The study found that the drug caused the incidence of cough ≥ 1%. The authors retrospectively analyzed the incidence of cough caused by the drug, clinical features and prognosis. Patients and Methods The authors enumerated 209 cases of enalapril treated in the previous three years as subjects. All patients were followed up for at least 3 months after the start of enalapril treatment. Through access to medical records and telephone contact with patients