又称钙拮抗剂。众所周知,钙离子为兴奋-收缩耦联中主要联系物质,对心肌、骨骼肌和血管平滑肌的收缩具有重要作用,而钙通道阻滞剂能阻断钙离子的上述作用,影响动作电位曲线的第2位相,具有降低心肌收缩力,延长房室结传导时间和房室结不应期,解除血管痉挛,松弛血管平滑肌致使血管扩张等作用。目前所知的钙 Also known as calcium antagonist. It is well-known that calcium ion is the main contact substance in excitatory-contractive coupling, which plays an important role in the contraction of myocardium, skeletal muscle and vascular smooth muscle. However, calcium channel blockers can block the above-mentioned action of calcium ion, 2 phase, with reduced myocardial contractility, prolongation of atrioventricular node conduction time and atrioventricular node refractory period, relieve vasospasm, relaxation of vascular smooth muscle resulting in vasodilation and so on. Calcium is known to date