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目的观察普罗帕酮伍用稳心颗粒治疗各类早搏疗效及其不良反应。方法选择68例早搏患者随机分成治疗组(34例)和对照组(34例),2组均服用治疗基础疾病的药物,治疗组给予稳心颗粒9g和普罗帕酮150mg,每日3次,温开水口服,4周为1疗程;对照组给予普罗帕酮150mg每日3次口服。均4周为1疗程,服药后每周查心电图1次。结果临床症状改善治疗组总有效率优于对照组(91.18%vs76.47%,P<0.05);心电图疗效评价治疗组总有效率优于对照组(88.24%vs70.59%,P<0.05)。结论抗心律失常药普罗帕酮伍用稳心颗粒,对各类早搏均有明显疗效,可改善患者临床症状,副作用小。
Objective To observe the efficacy and adverse reactions of propafenone combined with Wenxin Granule in treating all kinds of premature beats. Methods Sixty-eight patients with premature beats were randomly divided into treatment group (34 cases) and control group (34 cases). Both groups were treated with drugs for treating basic diseases. The treatment group was given 9g of Wenxin Granule and 150mg of propafenone, three times daily, Warm water oral administration, 4 weeks for a course of treatment; the control group was given propafenone 150mg orally 3 times a day. 4 weeks for a course of treatment, check the ECG once a week after taking the drug. Results The total effective rate in the treatment group was better than that in the control group (91.18% vs 76.47%, P <0.05). The total effective rate in the treatment group was significantly higher than that in the control group (88.24% vs 70.59%, P <0.05) . Conclusions propafenone, an antiarrhythmic drug, has significant curative effect on all kinds of premature beats with Wenxin Granule, which can improve clinical symptoms and side effects of patients.