例1:女,39岁。生后8个月起面部陆续出现绿豆大小的淡红色丘疹,以后全身出现大小不一的褐色丘疹,无自觉症状。智力正常。无癫痫史。体检:心率80次/分,二尖瓣区可闻及Ⅲ级吹风样收缩期杂音。余无异常。皮科所见:面部有绿豆大的坚韧丘疹,以鼻唇沟、两颊及下颌尤著。鼻翼两侧紫红 Example 1: Female, 39 years old. 8 months after birth from the face appeared green bean size pink papules, after the body appeared brown papules of varying sizes, no symptoms. Mental normal. No history of epilepsy. Physical examination: heart rate 80 beats / min, mitral valve area can be heard and Ⅲ grade hair-style systolic murmur. I no exception. Pico saw: the face of a large tough mung bean mush to the nasolabial fold, especially cheek and jaw. Red nose on both sides