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引流熊胆Ｉｇ能明显地抑制二甲苯、巴豆油所致小鼠耳壳肿胀．抑制小鼠腹腔毛细血管通透性．抑制角叉菜胶所致大鼠足肿胀及Ｐｒｅｕｎｄ完全性剂所致大鼠关节炎；对肾上腺、胸腺、脾脏及淋巴结重量无明显影响。抑制小鼠棉球肉芽肿增生，抑制小鼠单核巨噬细胞吞噬功能。表明引流熊胆具有抑制急、慢性及免疫性炎症作用和免疫抑制作用。引流熊胆还抑制大鼠热烫足肿胀．减少大鼠炎症部位ＰＧＥ２含量。提示引流熊胆的抗炎作用与抑制炎症部位的激肽类和ＰＧＥ２的合成与释放有关。
Gallbladder Ig can significantly inhibit xylene, croton oil-induced mouse ear swelling. Inhibit mouse peritoneal capillary permeability. Inhibition of carrageenan-induced foot swelling in rats and Preund complete agent-induced arthritis in rats; on the adrenal gland, thymus, spleen and lymph node weight had no significant effect. Inhibit the proliferation of mouse granuloma of cotton and inhibit the phagocytosis of mouse monocyte-macrophage. Show that the drainage of bear gall can inhibit acute, chronic and immune inflammation and immunosuppressive effects. Gallbladder also inhibits heat-induced foot swelling in rats. Reduce the PGE2 content in the inflammation site of rats. It is suggested that the anti-inflammatory effect of the cryogenic gall bladder is related to the inhibition of the synthesis of kinins and the synthesis and release of PGE2 at the inflammatory site.