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一、流行病学及临床表现1.流行病学据1988~1989年发生的院内感染表明,在244名入院病例中,除去入院数日后转科或因别的原因死亡的44例外,还有200例的研究对象。在200例中,有8例在入院时就已经是MRSA阳性,而且每例都是从产科来的入院儿。除去这8例余192例中,有100例(52.1%)在住院过程中发生了感染。对携有MRSA(包括发病例)和未携有MRSA的婴儿的几点背景因素加以比较发现,以体重不到1500克的早产儿寄居率比较高,一般认为,这与接受人工换气的婴儿的寄居率相对高有一定关连。另外,在未寄居MRSA的婴儿的鼻粘膜上表皮葡萄球菌或MRSA的寄居率却相对较高。抗菌素(除去为治疗MSSA感染为目的)的使用,在这些病例中并没有成为易于
I. Epidemiology and clinical manifestations 1. Epidemiology According to the nosocomial infections that occurred from 1988 to 1989, among the 244 admitted patients, 44 were admitted to the hospital or died of other causes a few days after admission Example of the research object. Of the 200 patients, 8 were admitted to hospital at the time of admission to the hospital and were admitted to hospital from obstetricians. Among the 192 cases except 8 cases, 100 cases (52.1%) were infected during hospitalization. Comparisons of several background factors between MRSA (including incidental) and non-MRSA infants found that occupancy rates were higher in preterm infants weighing less than 1500 grams, which is generally considered to be associated with ventilatory infants The relatively high occupancy rate has a certain relationship. In addition, nasal mucosal S. epidermidis or MRSA rates are relatively high in infants who do not colonize MRSA. The use of antibiotics (except for the purpose of treating MSSA infections) did not become easy in these cases