目的观察右旋糖酐４０与强力宁对儿童肾病综合征（ＮＳ）合并水肿的疗效。方法Ａ组采用右旋糖酐４０加强力宁 ２ ｍｌ／ｋｇ静脉滴注， １次／ｄ， １０ ｄ为一疗程； Ｂ组采用 ２０％白蛋白静滴。结果 Ａ组患儿在水肿消退、尿蛋白转阴及血生化指标恢复方面均优于Ｂ组。结论右旋糖酐４０是取代白蛋白治疗肾病水肿更为安全、有效、经济的药物。 Objective To observe the effect of dextran 40 and Qianglinning on children with nephrotic syndrome (NS) complicated with edema. Methods A group of 40 dextran plus nifedipine 2 ml / kg intravenous infusion, 1 / d, 10 d for a course of treatment; B group with 20% albumin intravenous infusion. Results A group of children in the edema, urine protein negative and blood biochemical indicators were better than the B group. Conclusion Dextran 40 is a safer, more effective and economical alternative to albumin in the treatment of nephrotic edema.