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目的分析三维适形放疗治疗晚期胰腺癌的疗效。方法33例晚期胰腺癌经临床确诊不能手术患者采用三维适形放射治疗,单次剂量2.5～3Gy,每日一次,(DT)55～60Gy。结果放疗后1个月～3个月,经CT、MRI复查肿瘤局部缓解率(CR+PR)为69.7%,其中2例完全缓解,21例部分缓解;疼痛缓解率(CR+PR)为90.91%;黄疸消退率(CR+PR)为83.33%;1、2年生存率分别为57.58%(19/33)、21.21%(7/33);中位生存期15.5个月,副反应可以耐受。结论三维适形放疗治疗晚期胰腺癌姑息止痛效果好,退黄作用快,能延长生存期,提高生活质量。
Objective To analyze the curative effect of three-dimensional conformal radiotherapy for advanced pancreatic cancer. Methods Thirty-three patients with advanced pancreatic cancer who were clinically diagnosed as inoperable were treated with three-dimensional conformal radiotherapy at a single dose of 2.5-3 Gy daily (DT) of 55-60 Gy. Results One month to three months after radiotherapy, the tumor response rate (CR + PR) was 69.7% by CT and MRI, of which 2 patients were completely relieved and 21 patients partially relieved. The CR + PR was 90.91 %. The CR + PR was 83.33%. The 1-year and 2-year survival rates were 57.58% (19/33) and 21.21% (7/33), respectively. The median survival time was 15.5 months. By Conclusion Three-dimensional conformal radiotherapy for advanced pancreatic cancer palliative analgesic effect is good, the role of jaundice, can extend the survival and improve quality of life.