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目的分析广西壮族自治区(广西)2013年疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征,评价广西AEFI监测系统运转情况。方法通过疑似预防接种异常反应监测信息管理系统收集2013年广西报告的AEFI个案数据,采用描述性方法进行流行病学分析。结果 2013年广西报告AEFI个案1050例,广西113个县(区、市)均有AEFI数据报告,县级覆盖率为100%,48 h报告率为95.62%,48 h调查率为98.98%。男女性别比为1.71∶1;根据广西2013年免疫规划信息系统中疫苗接种剂次估算,总的报告发生率为4.18/10万剂次,非严重AEFI报告发生率为4.07/10万剂次,严重AEFI报告发生率为0.11/10万剂次。预防接种异常反应报告发生率为1.50/10万剂次。异常反应的临床诊断以过敏性皮疹、卡介苗淋巴结炎为主。在所有的AEFI中,治愈和好转的占98.67%。结论广西的AEFI监测系统运转正常,要加强AEFI因果关联评估、分类及处理等相关知识的培训工作,确保AEFI监测数据的质量。
Objective To analyze the occurrence characteristics of suspected AEFI in Guangxi Zhuang Autonomous Region (Guangxi) in 2013 and evaluate the operation of Guangxi AEFI monitoring system. Methods The AEFI case data collected in Guangxi in 2013 was collected through the information system of suspected antivirus reaction monitoring information, and the descriptive method was used for epidemiological analysis. Results AEFI was reported in 1050 cases in Guangxi in 2013 and AEFI data in 113 counties (autonomous regions and municipalities) in Guangxi. The coverage rate at county level was 100%. The reporting rate was 95.62% at 48 hours and 98.98% at 48 hours. The sex ratio of men to women was 1.71:1. According to the vaccination dose estimates in the immunization planning information system of Guangxi in 2013, the total reported rate was 4.18 / 100,000 and the non-serious AEFI was 4.07 / 100,000. The incidence of severe AEFI was 0.11 / 100,000 doses. The incidence of abnormal vaccination reporting was 1.50 / 100,000 doses. Clinical diagnosis of anaphylaxis allergic rash, BCG-based lymphadenitis. Among all AEFIs, 98.67% were cured and improved. Conclusion The AEFI monitoring system in Guangxi is in normal operation. Training on related knowledge such as assessment, classification and treatment of AEFI causality should be strengthened to ensure the quality of AEFI monitoring data.