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目的 利用近红外光谱监测系统(near infrared spectroscopy,NIRS)定量研究腓骨瓣移植后腓骨血氧饱和度的变化规律. 方法 行腓骨肌皮瓣修复下颌骨的患者36例,常规以NIRS检测腓骨肌皮瓣术前及术后8 d内的血氧饱和度变化.移植前后患侧为手术组,同一患者手术对侧下颌骨为对照组. 结果 35例腓骨肌皮瓣移植成功,1例因静脉血栓致移植失败.修复成功的35例中,术后144 h前,手术组血氧饱和度均低于对照组1.9%～5.7%;术后144 h后,手术组与对照组血氧饱和度差异不明显,均约63.0%.移植失败腓骨早期,NIPS显示血氧饱和度明显降低. 结论 NIRS可无创监测埋藏腓骨瓣的血氧饱和度,真实地反映深部游离移植组织血运状况.腓骨移植后短期内血氧饱和度降低,移植术后7 d恢复至正常.“,”Objective To study the change of tissue oxygen index (TOI) by non-invasive near infrared spectroscopy (NIRS) and to investigate the blood flow variety of fibula flaps after operation. Methods Thirty-six patients who accepted fibula flap reconstruction were chosen as subjects. Authors measured the TOI of the fibula flaps and the control side every four hours in the first twenty-four hours, and measured these positions with the intermittence of twelve hours from second to eighth day after operation. Results Thirty-five flaps were successful and one failed. The TOI of fibula flaps shortly after operation was significantly lower than that before the operation(P <0. 05). In the successful cases the TOI of fibula flaps and the control sides was fluctuated from 50. 0% to 72. 0%. The TOI of fibula flaps was significantly lower than that of the control sides within 144 hours after operation(P <0. 05). After 144 hours the TOI was equal to that of the control side. TOI of the failed ease decreased dramatically. Conclusions NIRS can reliably indicate the change of TOI in buried flaps and detect ischemia at the early stage. The TOI of the fibula flaps depress at the early stage and returns to normal at 144 hours after operation.