孤独症谱系障碍(ASD)是广义上的孤独症,已经成为儿童致残的主要精神类疾病之一。基于谷氨酸能、多巴胺能、抗氧化和抗炎机制,以及国外临床实践,N-乙酰半胱氨酸治疗ASD症状的作用得到肯定。本文综述N-乙酰半胱氨酸治疗ASD症状的作用机制和临床实践新进展。 Autism Spectrum Disorder (ASD) is a generalized autism that has become one of the major psychiatric disorders of children’s disability. Based on glutamatergic, dopaminergic, anti-oxidant and anti-inflammatory mechanisms, as well as foreign clinical practice, the role of N-acetylcysteine ​​in the treatment of ASD symptoms is affirmed. This article reviews the mechanism of N-acetyl cysteine ​​in the treatment of ASD symptoms and clinical practice.